Facility ID: 9050WPLYPP365MA
Facility Name and Address: POLYPEPTIDE LABORATORIES INC. 365 MAPLE AVE TORRANCE, CA 90503 Parent Company: POLYPEPTIDE LABORATORIES INC Industry: Pharmaceutical Preparation Manufacturing (325412) Chemical: N,N-Dimethylformamide |
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Reporting Year | Section 8.10: Newly Implemented Source Reduction Activity | Section 8.10: Methods to Identify Activity | Section 8.11: Optional Pollution Prevention Information* |
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2022 |
Source Reduction:: S21: Optimized process conditions to increase efficiency
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Methods to Identify SR Opportunities: T04: Participative team management
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2021 |
Source Reduction:: S21: Optimized process conditions to increase efficiency
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Methods to Identify SR Opportunities: T01: Internal pollution prevention opportunity audit(s)
Methods to Identify SR Opportunities: T04: Participative team management |
S21: PolyPeptide has an active ongoing program to optimize the utilization of Dimethylformamide. |
2020 |
Source Reduction:: W50: Optimized reaction conditions or otherwise increased efficiency of synthesis
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Methods to Identify SR Opportunities: T01: Internal pollution prevention opportunity audit(s)
Methods to Identify SR Opportunities: T04: Participative team management |
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2019 |
Source Reduction:: W50: Optimized reaction conditions or otherwise increased efficiency of synthesis
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Methods to Identify SR Opportunities: T04: Participative team management
Methods to Identify SR Opportunities: T01: Internal pollution prevention opportunity audit(s) |
W50: Dimethylformamide (DMF) is largest volume solvent that the PolyPeptide (PPL) Group currently employs in its manufacturing process. Through a combination of better washing efficiency, reuse and process analytics PPL aims to reduce DMF consumption by >25%. Source Reduction - Dimethylformamide (DMF) is largest volume solvent that the PolyPeptide (PPL) Group currently employs in its manufacturing process. Through a combination of better washing efficiency, reuse and process analytics PPL aims to reduce DMF consumption by >25%. |
2018 |
Barriers: B5-Barriers to P2 B5 - Specific regulatory/permit burdens.
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Barriers to P2: B5 - Specific regulatory/permit burdens. - FDA approved production process. Changes must be approved by FDA. |
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2016 |
Source Reduction:: W32: Improved procedures for loading, unloading, and transfer operations
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Methods to Identify SR Opportunities: T10: Vendor assistance
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2015 |
Source Reduction:: W50: Optimized reaction conditions or otherwise increased efficiency of synthesis[-0-4%]
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Methods to Identify SR Opportunities: T04: Participative team management
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Source Reduction - Our clients are changing their BOC chemistry to FMOC chemistry where possible at the outset of drug development which can reduce certain hazardous reactants with less hazardous reactants.. |
2014 |
Source Reduction:: W15: Introduced an in-line product quality monitoring or other process analysis system
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Methods to Identify SR Opportunities: T01: Internal pollution prevention opportunity audit(s)
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2013 |
Source Reduction:: W19: Other changes in operating practices
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Methods to Identify SR Opportunities: T04: Participative team management
Methods to Identify SR Opportunities: T06: Employee recommendation (under a formal company program) Methods to Identify SR Opportunities: T11: Other |
W19: The company is utilizing lean manufacturing principles. Source Reduction - Continuous improvement is encouraged in all work procedures. Source Reduction - Daily production scheduling meetings are held to address immediate concerns in addition to weekly project meetings which are held to plan longer term projects and actions. Barriers to P2 - Recycling statements for TRI section 8.11Polypeptide Laboratories produces customized Polypeptides for drug formulation for major pharmaceutical corporations. Each formulation requires pure reagents, thus no recycling can be attempted for reagents. |
2012 |
Source Reduction:: W19: Other changes in operating practices
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Methods to Identify SR Opportunities: T04: Participative team management
Methods to Identify SR Opportunities: T06: Employee recommendation (under a formal company program) Methods to Identify SR Opportunities: T11: Other |
W19: Implementation of lean manufacturing to optimize operation cost and bottle necks in production workflow Source Reduction - Continuous improvement Source Reduction - Suggestions on increasing production efficiency Source Reduction - Internal meeting to optimize operation costs, reduce waste and costs |
The Waste Management Hierarchy |
The waste management hierarchy established by the Pollution Prevention Act (PPA) guides waste generators toward the best options for managing wastes.
The preferred option is to prevent pollution at its source, but for waste that is generated, the preferred management methods are recycling, followed
by burning for energy recovery, treatment and, as a last resort, disposing of the waste.
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